Demo Datasets

Curated transcriptomics datasets paired with recommended molecular AOPs. Pick one to load it into the analyser with the AOPs already selected.

PXR Agonists — Liver Steatosis

Two reference datasets where liver cells were exposed to PXR-activating compounds. Recommended AOP: AOP:1 (PXR activation leading to liver steatosis).

PXR agonist 1 (GSE90122_TO90137)

Reference dataset simulating exposure to a prototypical PXR activator.

PXR agonist 2 (GSE90122_SR12813)

A second compound activating the same nuclear receptor, with a distinct gene profile.

Compare both PXR datasets

Run both agonists together as a batch against AOP:DEMO with a harmonised gene background, then open the side-by-side comparison (heatmap, table, network, and shared driver genes). Takes a few seconds.