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This tool is under development, results and interface are subject to change

Molecular Adverse Outcome Pathway Analyser

Molecular AOP Analyser Demo

To get started quickly, choose one of the demo gene expression datasets below. These represent experiments where cells were exposed to chemicals, and the resulting gene expression changes can be analyzed in the context of molecular AOPs. The datasets have been pre-processed.

(In a real case, you'd upload your own data instead.)

  • PXR agonist 1 (GSE90122_TO90137): A reference dataset simulating exposure to a prototypical PXR activator.
  • PXR agonist 2 (GSE90122_SR12813): A second compound activating the same nuclear receptor, with a distinct gene profile.

After selecting a dataset, the tool will guide you through:

  • Choosing the correct data columns
  • Visualizing gene expression changes (volcano plot)
  • Running KE enrichment analysis and explore the molecular AOP network

Select Demo Dataset